FBXL2 antibody (AA 120-240)

Catalog No. ABIN6140508

Product Details anti-FBXL2 Antibody

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Binding Specificity: AA 120-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: STCYSLSRFC SKLKHLDLTS CVSITNSSLK GISEGCRNLE YLNLSWCDQI TKDGIEALVR GCRGLKALLL RGCTQLEDEA LKHIQNYCHE LVSLNLQSCS RITDEGVVQI CRGCHRLQAL C

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-240 of human FBXL2 (NP_036289.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBXL2

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Alternative Name: FBXL2 (FBXL2 Products)

Synonyms: FBL2 antibody, FBL3 antibody, 2810423A21Rik antibody, Fbl3 antibody, RGD1562243 antibody, fbxl20 antibody, sb:cb783 antibody, zgc:73374 antibody, Fbl2 antibody, Fbxl2 antibody, F-box and leucine rich repeat protein 2 antibody, F-box and leucine-rich repeat protein 2 antibody, F-box and leucine-rich repeat protein 20 antibody, FBXL2 antibody, Fbxl2 antibody, fbxl2 antibody, Fbxl20 antibody

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FBXL2,FBL2,FBL3,FBXL2

Molecular Weight: 39 kDa/47 kDa

Gene ID: 25827

UniProt: Q9UKC9