GLIS3 antibody

Catalog No. ABIN7862708

The Mouse Monoclonal anti-GLIS3 antibody is suitable to detect GLIS3 in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for GLIS3 antibody (ABIN7862708)

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLIS3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: PCRP-GLIS3-1B11

Product Details anti-GLIS3 Antibody

Purpose: GLIS family zinc finger 3 (GLIS3) / ZNF515 Antibody

Specificity: GLIS3 is a member of the GLI similar zinc finger protein family, and encodes a nuclear protein with five C2H2 type zinc finger domains. It functions as both an activator and repressor of transcription, and is specifically involved in the development of pancreatic beta cells, thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full length nature of only two have been determined.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GLIS3 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Alternative Name: GLIS family zinc finger 3

Background:

FLJ38999, FLJ90578, GLI similar 3, GLI SIMILAR PROTEIN 3, GLIS family zinc finger 3, MGC33662, OK/KNS-cl.4, Zinc finger protein 515, Zinc finger protein GLIS3, ZNF515

A549 or U-2 OS cells.

Molecular Weight: 84kDa

Gene ID: 169792, 162125

UniProt: Q8NEA6