GNAI3 antibody (AA 1-354)

Catalog No. ABIN6141204

Product Details anti-GNAI3 Antibody

Target: GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))

Binding Specificity: AA 1-354

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAI3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: MGCTLSAEDK AAVERSKMID RNLREDGEKA AKEVKLLLLG AGESGKSTIV KQMKIIHEDG YSEDECKQYK VVVYSNTIQS IIAIIRAMGR LKIDFGEAAR ADDARQLFVL AGSAEEGVMT PELAGVIKRL WRDGGVQACF SRSREYQLND SASYYLNDLD RISQSNYIPT QQDVLRTRVK TTGIVETHFT FKDLYFKMFD VGGQRSERKK WIHCFEGVTA IIFCVALSDY DLVLAEDEEM NRMHESMKLF DSICNNKWFT ETSIILFLNK KDLFEEKIKR SPLTICYPEY TGSNTYEEAA AYIQCQFEDL NRRKDTKEIY THFTCATDTK NVQFVFDAVT DVIIKNNLKE CGLY

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human GNAI3 (NP_006487.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GNAI3

Target: GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))

Alternative Name: GNAI3 (GNAI3 Products)

Synonyms: AI158965 antibody, AW537698 antibody, Galphai3 antibody, Gnai-3 antibody, 87U6 antibody, ARCND1 antibody, GIP3A antibody, G protein subunit alpha i3 antibody, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 antibody, guanine nucleotide binding protein (G protein), alpha inhibiting 3 antibody, G protein subunit alpha i3 S homeolog antibody, GNAI3 antibody, gnai3 antibody, Gnai3 antibody, gnai3.S antibody

Background: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.,GNAI3,87U6,ARCND1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,mTOR Signaling Pathway,Phospholipase Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,GNAI3

Molecular Weight: 40 kDa

Gene ID: 2773

UniProt: P08754

Pathways: cAMP Metabolic Process, G-protein mediated Events