Serotonin Receptor 3A antibody (AA 24-241)

Catalog No. ABIN6142072

This Rabbit Polyclonal antibody specifically detects Serotonin Receptor 3A in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Serotonin Receptor 3A antibody (AA 24-241) (ABIN6142072)

Target: Serotonin Receptor 3A (HTR3A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Serotonin Receptor 3A Antibody

Binding Specificity: AA 24-241

Sequence: LAQGEARRSR NTTRPALLRL SDYLLTNYRK GVRPVRDWRK PTTVSIDVIV YAILNVDEKN QVLTTYIWYR QYWTDEFLQW NPEDFDNITK LSIPTDSIWV PDILINEFVD VGKSPNIPYV YIRHQGEVQN YKPLQVVTAC SLDIYNFPFD VQNCSLTFTS WLHTIQDINI SLWRLPEKVK SDRSVFMNQG EWELLGVLPY FREFSMESSN YYAEMKFY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-241 of human HTR3A (NP_000860.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Alternative Name: HTR3A

Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.,HTR3A,5-HT-3,5-HT3A,5-HT3R,5HT3R,HTR3,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,Cell Type Marker,Neuron marker,HTR3A

Molecular Weight: 53 kDa/55 kDa/58 kDa/59 kDa

Gene ID: 3359

UniProt: P46098

Pathways: Synaptic Membrane