KREMEN1 antibody (AA 180-380)

Catalog No. ABIN6143005

This Rabbit Polyclonal antibody specifically detects KREMEN1 in WB. It exhibits reactivity toward Human.

Quick Overview for KREMEN1 antibody (AA 180-380) (ABIN6143005)

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KREMEN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KREMEN1 Antibody

Binding Specificity: AA 180-380

Sequence: YGEAASTECN SVCFGDHTQP CGGDGRIILF DTLVGACGGN YSAMSSVVYS PDFPDTYATG RVCYWTIRVP GASHIHFSFP LFDIRDSADM VELLDGYTHR VLARFHGRSR PPLSFNVSLD FVILYFFSDR INQAQGFAVL YQAVKEELPQ ERPAVNQTVA EVITEQANLS VSAARSSKVL YVITTSPSHP PQTVPGWTVY G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human KREMEN1 (NP_001034659.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KREMEN1

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Alternative Name: KREMEN1

Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.,KREMEN1,ECTD13,KREMEN,KRM1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Stem Cells,KREMEN1

Molecular Weight: 50 kDa/51 kDa/53 kDa

Gene ID: 83999

UniProt: Q96MU8

Pathways: WNT Signaling