LEPREL1 antibody (AA 400-700)

Catalog No. ABIN6143146

This anti-LEPREL1 antibody is a Rabbit Polyclonal antibody detecting LEPREL1 in WB. Suitable for Human.

Quick Overview for LEPREL1 antibody (AA 400-700) (ABIN6143146)

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEPREL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LEPREL1 Antibody

Binding Specificity: AA 400-700

Sequence: IRYGGRQDEN RVPSGVNVEG AEVHGFSMGK KLSPKIDRDL REGGPLLYEN ITFVYNSEQL NGTQRVLLDN VLSEEQCREL HSVASGIMLV GDGYRGKTSP HTPNEKFEGA TVLKALKSGY EGRVPLKSAR LFYDISEKAR RIVESYFMLN STLYFSYTHM VCRTALSGQQ DRRNDLSHPI HADNCLLDPE ANECWKEPPA YTFRDYSALL YMNDDFEGGE FIFTEMDAKT VTASIKPKCG RMISFSSGGE NPHGVKAVTK GKRCAVALWF TLDPLYRELE RIQADEVIAI LDQEQQGKHE L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human LEPREL1 (NP_060662.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LEPREL1

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Alternative Name: LEPREL1

Background: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,P3H2,LEPREL1,MCVD,MLAT4,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Neuroscience,LEPREL1

Molecular Weight: 60 kDa/80 kDa

Gene ID: 55214

UniProt: Q8IVL5