MARCH9 antibody (AA 277-346)

Catalog No. ABIN6143553

Product Details anti-MARCH9 Antibody

Target: MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))

Binding Specificity: AA 277-346

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH9 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: GTAGKSGPRN SRTGPTSGAT SRPPAAQRMR TLLPQRCGYT ILHLLGQLRP PDARSSSHSG REVVMRVTTV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 277-346 of human MARCH9 (NP_612405.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MARCH9

Target: MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))

Alternative Name: 9-Mar (MARCH9 Products)

Synonyms: Rnf179 antibody, March-IX antibody, MARCH-IX antibody, RNF179 antibody, AI608492 antibody, BC019560 antibody, membrane associated ring-CH-type finger 9 antibody, membrane associated ring-CH-type finger 9 S homeolog antibody, membrane-associated ring finger (C3HC4) 9 antibody, March9 antibody, march9.S antibody, MARCH9 antibody, march9 antibody

Background: MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266], Hoer et al., 2007 [PubMed 17174307]).[supplied by OMIM, Apr 2010],MARCH9,MARCH-IX,RNF179,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,9-Mar

Molecular Weight: 25 kDa/37 kDa

Gene ID: 92979

UniProt: Q86YJ5