MEGF10 antibody (AA 26-160)

Catalog No. ABIN6143719

Product Details anti-MEGF10 Antibody

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Binding Specificity: AA 26-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEGF10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LNLEDPNVCS HWESYSVTVQ ESYPHPFDQI YYTSCTDILN WFKCTRHRVS YRTAYRHGEK TMYRRKSQCC PGFYESGEMC VPHCADKCVH GRCIAPNTCQ CEPGWGGTNC SSACDGDHWG PHCTSRCQCK NGALC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-160 of human MEGF10 (NP_001295048.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MEGF10

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Alternative Name: MEGF10 (MEGF10 Products)

Synonyms: EMARDD antibody, 3000002B06Rik antibody, Gm331 antibody, multiple EGF-like domains 10 antibody, multiple EGF like domains 10 antibody, multiple EGF-like-domains 10 antibody, Megf10 antibody, MEGF10 antibody

Background: This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.,MEGF10,EMARDD,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Stem Cells,Mesenchymal Stem Cells,MEGF10

Molecular Weight: 60 kDa/122 kDa

Gene ID: 84466

UniProt: Q96KG7

Pathways: Regulation of Muscle Cell Differentiation