MYLK3 antibody (AA 1-240)

Catalog No. ABIN6144266

This Rabbit Polyclonal antibody specifically detects MYLK3 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for MYLK3 antibody (AA 1-240) (ABIN6144266)

Target: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYLK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MYLK3 Antibody

Binding Specificity: AA 1-240

Sequence: MSGTSKESLG HGGLPGLGKT CLTTMDTKLN MLNEKVDQLL HFQEDVTEKL QSMCRDMGHL ERGLHRLEAS RAPGPGGADG VPHIDTQAGW PEVLELVRAM QQDAAQHGAR LEALFRMVAA VDRAIALVGA TFQKSKVADF LMQGRVPWRR GSPGDSPEEN KERVEEEGGK PKHVLSTSGV QSDAREPGEE SQKADVLEGT AERLPPIRAS GLGADPAQAV VSPGQGDGVP GPAQAFPGHL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human MYLK3 (NP_872299.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MYLK3

Target: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Alternative Name: MYLK3

Background: Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008],MYLK3,MLCK,MLCK2,caMLCK,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,Cardiovascular,Heart,Contractility,MYLK3

Molecular Weight: 52 kDa/88 kDa

Gene ID: 91807

UniProt: Q32MK0

Pathways: Regulation of Muscle Cell Differentiation