NPHP4 antibody (AA 1247-1426)

Catalog No. ABIN6144772

Product Details anti-NPHP4 Antibody

Target: NPHP4 (Nephronophthisis 4 (NPHP4))

Binding Specificity: AA 1247-1426

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RLSLVLRGTQ TVRKVRAFTS HPQELKTDPK GVFVLPPRGV QDLHVGVRPL RAGSRFVHLN LVDVDCHQLV ASWLVCLCCR QPLISKAFEI MLAAGEGKGV NKRITYTNPY PSRRTFHLHS DHPELLRFRE DSFQVGGGET YTIGLQFAPS QRVGEEEILI YINDHEDKNE EAFCVKVIYQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1247-1426 of human NPHP4 (NP_055917.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NPHP4

Target: NPHP4 (Nephronophthisis 4 (NPHP4))

Alternative Name: NPHP4 (NPHP4 Products)

Synonyms: NPHP4 antibody, POC10 antibody, SLSN4 antibody, 4930564O18Rik antibody, nmf192 antibody, nephrocystin 4 antibody, nephrocystin-4 antibody, nephronophthisis 4 (juvenile) homolog (human) antibody, NPHP4 antibody, LOC100184720 antibody, Nphp4 antibody

Background: This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.,NPHP4,POC10,SLSN4,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Tight Junctions,Cytoskeleton,NPHP4

Molecular Weight: 99 kDa/157 kDa

Gene ID: 261734

UniProt: O75161