Poliovirus Receptor antibody (AA 220-345)

Catalog No. ABIN6146508

This Rabbit Polyclonal antibody specifically detects Poliovirus Receptor in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Poliovirus Receptor antibody (AA 220-345) (ABIN6146508)

Target: Poliovirus Receptor (PVR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Poliovirus Receptor Antibody

Binding Specificity: AA 220-345

Sequence: TCKVEHESFE KPQLLTVNLT VYYPPEVSIS GYDNNWYLGQ NEATLTCDAR SNPEPTGYNW STTMGPLPPF AVAQGAQLLI RPVDKPINTT LICNVTNALG ARQAELTVQV KEGPPSEHSG MSRNAI

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-345 of human CD155/PVR (NP_006496.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: PVR

Background: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.,PVR,CD155,HVED,NECL5,Necl-5,PVS,TAGE4,Immunology & Inflammation,CD markers,PVR

Molecular Weight: 39 kDa/40 kDa/42 kDa/45 kDa

Gene ID: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome