RUNX3 antibody (AA 210-429)

Catalog No. ABIN6147314

This anti-RUNX3 antibody is a Rabbit Polyclonal antibody detecting RUNX3 in WB and IF. Suitable for Human.

Quick Overview for RUNX3 antibody (AA 210-429) (ABIN6147314)

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RUNX3 Antibody

Binding Specificity: AA 210-429

Sequence: DRFGDLERLR MRVTPSTPSP RGSLSTTSHF SSQPQTPIQG TSELNPFSDP RQFDRSFPTL PTLTESRFPD PRMHYPGAMS AAFPYSATPS GTSISSLSVA GMPATSRFHH TYLPPPYPGA PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT SSAASVAAGN LMNPSLGGQS DGVEADGSHS NSPTALSTPG RMDEAVWRPY

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-429 of human RUNX3 (NP_001026850.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3

Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.,RUNX3,AML2,CBFA3,PEBP2aC,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,Target gene,RUNX3

Molecular Weight: 44 kDa/45 kDa

Gene ID: 864

UniProt: Q13761