SLC1A1 antibody (AA 430-524)

Catalog No. ABIN6147868

Product Details anti-SLC1A1 Antibody

Target: SLC1A1 (Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1))

Binding Specificity: AA 430-524

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: AEDVTLIIAV DWLLDRFRTM VNVLGDAFGT GIVEKLSKKE LEQMDVSSEV NIVNPFALES TILDNEDSDT KKSYVNGGFA VDKSDTISFT QTSQF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 430-524 of human SLC1A1 (NP_004161.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC1A1

Target: SLC1A1 (Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1))

Alternative Name: SLC1A1 (SLC1A1 Products)

Synonyms: GB16911 antibody, EAAT3 antibody, SLC1A2a antibody, zgc:91959 antibody, EAAC1 antibody, SCZD18 antibody, D130048G10Rik antibody, EAAC2 antibody, MEAAC1 antibody, Eaac1 antibody, Eaat3 antibody, REAAC1 antibody, excitatory amino acid transporter 3 antibody, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody, solute carrier family 1 member 1 antibody, LOC412382 antibody, slc1a1 antibody, SLC1A1 antibody, CpipJ_CPIJ000674 antibody, CpipJ_CPIJ001134 antibody, Slc1a1 antibody

Background: This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.,SLC1A1,DCBXA,EAAC1,EAAT3,SCZD18,Neuroscience,SLC1A1

Molecular Weight: 57 kDa

Gene ID: 6505

UniProt: P43005

Pathways: Dicarboxylic Acid Transport