SMARCE1 antibody (AA 1-411)

Catalog No. ABIN6148115

Product Details anti-SMARCE1 Antibody

Target: SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))

Binding Specificity: AA 1-411

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR VTASSGITIP KPPKPPDKPL MPYMRYSRKV WDQVKASNPD LKLWEIGKII GGMWRDLTDE EKQEYLNEYE AEKIEYNESM KAYHNSPAYL AYINAKSRAE AALEEESRQR QSRMEKGEPY MSIQPAEDPD DYDDGFSMKH TATARFQRNH RLISEILSES VVPDVRSVVT TARMQVLKRQ VQSLMVHQRK LEAELLQIEE RHQEKKRKFL ESTDSFNNEL KRLCGLKVEV DMEKIAAEIA QAEEQARKRQ EEREKEAAEQ AERSQSSIVP EEEQAANKGE EKKDDENIPM ETEETHLEET TESQQNGEEG TSTPEDKESG QEGVDSMAEE GTSDSNTGSE SNSATVEEPP TDPIPEDEKK E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-411 of human BAF57/BAF57/SMARCE1 (NP_003070.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMARCE1

Target: SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))

Alternative Name: SMARCE1 (SMARCE1 Products)

Synonyms: BAF57 antibody, XBaf57 antibody, MGC52696 antibody, MGC69429 antibody, MGC81726 antibody, SMARCE1 antibody, DKFZp459O2235 antibody, fb54d11 antibody, wu:fb33d02 antibody, wu:fb54d11 antibody, Baf57 antibody, 2810417B20Rik antibody, 5830412H02Rik antibody, 9030408N19Rik antibody, Baf27 antibody, RGD1304726 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog antibody, smarce1 antibody, SMARCE1 antibody, smarce1.L antibody, Smarce1 antibody

Background: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.,SMARCE1,BAF57,CSS5,Epigenetics & Nuclear Signaling,Chromatin Remodeling,SMARCE1

Molecular Weight: 34 kDa/37 kDa/39 kDa/41 kDa/42 kDa/46 kDa

Gene ID: 6605

UniProt: Q969G3

Pathways: Chromatin Binding