beta Amyloid antibody

Catalog No. ABIN614819

The Mouse Monoclonal anti-beta Amyloid antibody is suitable to detect beta Amyloid in samples from Human. It has been validated for EIA and ELISA (Capture).

Quick Overview for beta Amyloid antibody (ABIN614819)

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta Amyloid antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), ELISA (Capture)

Clone: NT 4A2

Product Details anti-beta Amyloid Antibody

Sequence: DAEFRHDS

Specificity: This antibody recognizes the N-terminal sequence (DAEFRHDS) of beta Amyloid peptides, and full length beta Amyloid peptide 40, 42 and 43.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G

Immunogen: Full length Human beta amyloid peptide 43

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for beta Amyloid

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Alternative Name: Amyloid beta

Background: Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids. While the C-end amino acids showed no speciesspecificity in mammalians, the Nterminal amino acid sequences have minor discrepancies between difference species. Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer's disease. A recent study on A Aβ43 in brain showed that Aβ43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer's disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.

Gene ID: 351

Pathways: Inflammasome