SYCE1 antibody (AA 132-351)

Catalog No. ABIN6148756

This Rabbit Polyclonal antibody specifically detects SYCE1 in WB. It exhibits reactivity toward Human.

Quick Overview for SYCE1 antibody (AA 132-351) (ABIN6148756)

Target: SYCE1 (Synaptonemal Complex Central Element Protein 1 (SYCE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYCE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SYCE1 Antibody

Binding Specificity: AA 132-351

Sequence: ECKERISALN LQIEEEKNKQ RQLRLAFEEQ LEDLMGQHKD LWDFHMPERL AKEICALDSS KEQLLKEEKL VKATLEDVKH QLCSLCGAEG PSTLDEGLFL RSQEAAATVQ LFQEEHRKAE ELLAAAAQRH QQLQQKCQQQ QQKRQRLKEE LEKHGMQVPA QAQSTQEEEA GPGDVASPKP LKGERPGAAH QAGPDVLIGQ EDTLHPDLSP RGFQEIKELF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SYCE1

Target: SYCE1 (Synaptonemal Complex Central Element Protein 1 (SYCE1))

Alternative Name: SYCE1

Background: This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants.,SYCE1,C10orf94,CT76,POF12,SPGF15,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,SYCE1

Molecular Weight: 21 kDa/32 kDa/39 kDa

Gene ID: 93426

UniProt: Q8N0S2

Pathways: M Phase