TMPRSS2 antibody (AA 140-400)

Catalog No. ABIN6149286

The Rabbit Polyclonal anti-TMPRSS2 antibody has been validated for WB, IHC and IF. It is suitable to detect TMPRSS2 in samples from Human.

Quick Overview for TMPRSS2 antibody (AA 140-400) (ABIN6149286)

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TMPRSS2 Antibody

Binding Specificity: AA 140-400

Sequence: GLLWKFMGSK CSNSGIECDS SGTCINPSNW CDGVSHCPGG EDENRCVRLY GPNFILQVYS SQRKSWHPVC QDDWNENYGR AACRDMGYKN NFYSSQGIVD DSGSTSFMKL NTSAGNVDIY KKLYHSDACS SKAVVSLRCI ACGVNLNSSR QSRIVGGESA LPGAWPWQVS LHVQNVHVCG GSIITPEWIV TAAHCVEKPL NNPWHWTAFA GILRQSFMFY GAGYQVEKVI SHPNYDSKTK NNDIALMKLQ KPLTFNDLVK P

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-400 of human TMPRSS2 (NP_001128571.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Alternative Name: TMPRSS2

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,TMPRSS2,PP9284,PRSS10,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,TMPRSS2

Molecular Weight: 53 kDa/57 kDa

Gene ID: 7113

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interactome