UBE4A antibody (AA 797-1066)

Catalog No. ABIN6149841

Product Details anti-UBE4A Antibody

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Binding Specificity: AA 797-1066

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FLLDEAIQYL SKIKIQQIEK DRGEWDSLTP EARREKEAGL QMFGQLARFH NIMSNETIGT LAFLTSEIKS LFVHPFLAER IISMLNYFLQ HLVGPKMGAL KVKDFSEFDF KPQQLVSDIC TIYLNLGDEE NFCATVPKDG RSYSPTLFAQ TVRVLKKINK PGNMIMAFSN LAERIKSLAD LQQQEEETYA DACDEFLDPI MSTLMCDPVV LPSSRVTVDR STIARHLLSD QTDPFNRSPL TMDQIRPNTE LKEKIQRWLA ERKQQKEQLE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 797-1066 of human UBE4A (NP_001191006.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBE4A

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Alternative Name: UBE4A (UBE4A Products)

Synonyms: 4732444G18Rik antibody, 9930123J21Rik antibody, UFD2b antibody, ufd2 antibody, ubox2 antibody, E4 antibody, UBOX2 antibody, UFD2 antibody, Ab2-232 antibody, ubiquitination factor E4A S homeolog antibody, ubiquitination factor E4A antibody, ubiquitination factor E4A (UFD2 homolog, yeast) antibody, ubiquitin conjugation factor E4 A antibody, putative ubiquitination factor E4a antibody, ube4a.S antibody, Ube4a antibody, UBE4A antibody, ube4a antibody, LOC5563714 antibody, Smp_030780 antibody

Background: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,UBE4A,E4,UBOX2,UFD2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBE4A

Molecular Weight: 122 kDa/123 kDa

Gene ID: 9354

UniProt: Q14139