USP8 antibody (AA 1-270)

Catalog No. ABIN6150035

The Rabbit Polyclonal anti-USP8 antibody has been validated for WB and IF. It is suitable to detect USP8 in samples from Human.

Quick Overview for USP8 antibody (AA 1-270) (ABIN6150035)

Target: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-USP8 Antibody

Binding Specificity: AA 1-270

Sequence: MPAVASVPKE LYLSSSLKDL NKKTEVKPEK ISTKSYVHSA LKIFKTAEEC RLDRDEERAY VLYMKYVTVY NLIKKRPDFK QQQDYFHSIL GPGNIKKAVE EAERLSESLK LRYEEAEVRK KLEEKDRQEE AQRLQQKRQE TGREDGGTLA KGSLENVLDS KDKTQKSNGE KNEKCETKEK GAITAKELYT MMTDKNISLI IMDARRMQDY QDSCILHSLS VPEEAISPGV TASWIEAHLP DDSKDTWKKR GNVEYVVLLD WFSSAKDLQI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human USP8 (NP_005145.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for USP8

Target: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Alternative Name: USP8

Background: This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.,USP8,HumORF8,SPG59,UBPY,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,USP8

Molecular Weight: 115 kDa/127 kDa

Gene ID: 9101

UniProt: P40818