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TTR antibody
TTR
Reactivity: Human
IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-TTR Antibody
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Target
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TTR
(Transthyretin (TTR))
Reactivity
All reactivities for TTR antibodies
Human
Host
All hosts for TTR antibodies
Goat
Clonality
All clonalities for TTR antibodies
Polyclonal
Conjugate
All conjugates for TTR antibodies
This TTR antibody is un-conjugated
Application
All applications for TTR antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to Transthyretin (TTR).
Purification
Immunoaffinity Chromatography
Immunogen
TTR antibody was raised against purified human Prealbumin
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS, pH 7.2 containing 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TTR
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Target
TTR
(Transthyretin (TTR))
Alternative Name
Transthyretin / Prealbumin (TTR Products )
Synonyms
zgc:103583 antibody, TTR antibody, LOC100226992 antibody, CTS antibody, CTS1 antibody, HsT2651 antibody, PALB antibody, TBPA antibody, AA408768 antibody, AI787086 antibody, D17860 antibody, prealbumin antibody, Lr1 antibody, Tbpa antibody, Prealbumin antibody, xTTR antibody, transthyretin (prealbumin, amyloidosis type I) antibody, transthyretin antibody, Transthyretin antibody, transthyretin (prealbumin, amyloidosis type 1) antibody, transthyretin-like antibody, transthyretin L homeolog antibody, ttr antibody, TTR antibody, vpb38 antibody, MRAD2831_RS38185 antibody, Caci_4246 antibody, LOC100226992 antibody, Ttr antibody, ttr.L antibody
Background
Prealbumin, also known as transethrytin (TTR) is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.Synonyms: ATTR, PALP, TBPA, TTR
Gene ID
7276
NCBI Accession
NP_000362
UniProt
P02766
Pathways
Hormone Transport
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