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DDX58 antibody
DDX58
Reactivity: Human
IHC (p)
Host: Goat
Polyclonal
unconjugated
Product Details anti-DDX58 Antibody
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Target
See all DDX58 Antibodies
DDX58
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
Reactivity
All reactivities for DDX58 antibodies
Human
Host
All hosts for DDX58 antibodies
Goat
Clonality
All clonalities for DDX58 antibodies
Polyclonal
Conjugate
All conjugates for DDX58 antibodies
This DDX58 antibody is un-conjugated
Application
All applications for DDX58 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody reacts to RNA Helicase (RIG-I) (DDX58).
Purification
Purified
Immunogen
Synthetic peptide.
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline 0.5 mg/mL, 0.02 % Sodium Azide, pH 7.3, 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for DDX58
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Target
DDX58
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
Alternative Name
DDX58 (DDX58 Products )
Synonyms
RIG-I antibody, RIGI antibody, RLR-1 antibody, 6430573D20Rik antibody, C330021E21 antibody, RHIV-1 antibody, RIG-1 antibody, DExD/H-box helicase 58 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 antibody, DEXD/H-box helicase 58 antibody, DDX58 antibody, Ddx58 antibody
Background
EAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.Synonyms: DEAD box protein 58, DKFZp434J1111, DKFZp686N19181, FLJ13599, Probable ATP-dependent RNA helicase DDX58, RIG-1, RIG-I, Retinoic acid-inducible gene 1 protein
Gene ID
23586
NCBI Accession
NP_055129
UniProt
O95786
Pathways
Activation of Innate immune Response , Hepatitis C
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