Integrin Alpha2b antibody (Biotin)

Catalog No. ABIN6156522

This Mouse Monoclonal antibody specifically detects Integrin Alpha2b in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for Integrin Alpha2b antibody (Biotin) (ABIN6156522)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: ITGA2B-1036

Product Details anti-Integrin Alpha2b Antibody (Biotin)

Purpose: Mouse Monoclonal anti-CD41a (ITGA2B/1036), Biotin Conjugate

Characteristics: This antibody recognizes a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human Integrin alpha IIb protein

Isotype: IgG1 kappa

Application Details

Application Notes: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Comment:

KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41a

Background: BDPLT16, BDPLT2, GPalpha IIb, GT, HPA3, Integrin alpha IIb, ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex

Molecular Weight: 90 kDa

Gene ID: 3674, 411312

UniProt: P08514

Pathways: Integrin Complex