DPP4 antibody (CF®568)

Catalog No. ABIN6176440

The Mouse Monoclonal anti-DPP4 antibody has been validated for FACS, IHC (fro) and IF. It is suitable to detect DPP4 in samples from Human and Rat.

Quick Overview for DPP4 antibody (CF®568) (ABIN6176440)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DPP4 antibody is conjugated to CF®568

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: 202-36

Product Details anti-DPP4 Antibody (CF®568)

Purpose: Mouse Monoclonal anti-CD26 (202.36), CF568 Conjugate

Characteristics: This antibody recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human T cell clone

Isotype: IgG2b kappa

Application Details

Application Notes: Immunohistology Frozen Only 0.5-1.0 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Does not react with pig or sheep, others not tested
• Optimal dilution for a specific application should be determined by user

Comment:

YT, HEP-G2 cells, and lymphocytes. Lymph nodes and tonsils.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26

Molecular Weight: ~110 kDa

Gene ID: 1803, 368912

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity