CTNNA1 antibody

Catalog No. ABIN6178173

Product Details anti-CTNNA1 Antibody

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTNNA1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Purpose: Mouse Monoclonal anti-Catenin, alpha-1 (1G5), Purified, BSA-free

Characteristics: This antibody recognizes a protein of 102 kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2 -dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, ?-catenin forms a heterodimer with ?-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogen: Human alpha catenin fusion protein

Clone: 1G5

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Comment:

HeLa, A431 or MCF-7 Cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Preservative: Azide free

Target Details for CTNNA1

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Alternative Name: Catenin, alpha-1 (CTNNA1 Products)

Synonyms: CAP102 antibody, 2010010M04Rik antibody, AA517462 antibody, AI988031 antibody, Catna1 antibody, CG17947 antibody, CT39986 antibody, Dalpha-Cat antibody, Dalpha-cat antibody, DalphaC antibody, Dalphacat antibody, Dmcatp antibody, Dmel\\CG17947 antibody, a-Cat antibody, a-cat antibody, alpha-CAT antibody, alpha-cat antibody, alpha-catenin antibody, alpha-ctn antibody, alphaCAT antibody, alphaCat antibody, alphacat antibody, Alpha-Cat antibody, dgri_GLEANR_3829 antibody, DgriGH19548 antibody, GH19548 antibody, ctnna antibody, cap102 antibody, catna1 antibody, ctnna1 antibody, catenin alpha 1 antibody, catenin (cadherin associated protein), alpha 1 antibody, alpha Catenin antibody, catenin alpha-1 antibody, catenin (cadherin-associated protein), alpha 1 antibody, catenin alpha 1 S homeolog antibody, CTNNA1 antibody, Ctnna1 antibody, alpha-Cat antibody, Dgri\alpha-Cat antibody, Tsp_10127 antibody, ctnna1 antibody, ctnna1.S antibody

Background: Alpha E-catenin, Cadherin-associated protein, CAP102, Catenin alpha-1, CTNNA1, Renal carcinoma antigen NY-REN-13

Molecular Weight: 102 kDa

Gene ID: 1495, 445981

UniProt: P35221

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location