IFNA1 antibody (CF®488A)

Catalog No. ABIN6186594

This Mouse Monoclonal antibody specifically detects IFNA1 in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for IFNA1 antibody (CF®488A) (ABIN6186594)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA1 antibody is conjugated to CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 2-52

Product Details anti-IFNA1 Antibody (CF®488A)

Purpose: Mouse Monoclonal anti-Interferon alpha-1 (2.52), CF488A Conjugate

Characteristics: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified recombinant human IFN-alpha1

Isotype: IgG1 kappa

Application Details

Application Notes: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Comment:

Stimulated human peripheral blood mononuclear cells

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Alternative Name: Interferon alpha-1

Molecular Weight: 16-27 kDa

Gene ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signaling, Hepatitis C