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Spartan antibody (AA 1-240)
C1orf124
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Spartan Antibody
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Target
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Spartan (C1orf124)
(Chromosome 1 Open Reading Frame 124 (C1orf124))
Binding Specificity
All epitopes for Spartan antibodies
AA 1-240
Reactivity
All reactivities for Spartan antibodies
Human
Host
All hosts for Spartan antibodies
Rabbit
Clonality
All clonalities for Spartan antibodies
Polyclonal
Conjugate
All conjugates for Spartan antibodies
This Spartan antibody is un-conjugated
Application
All applications for Spartan antibodies
Western Blotting (WB)
Sequence
MDDDLMLALR LQEEWNLQEA ERDHAQESLS LVDASWELVD PTPDLQALFV QFNDQFFWGQ LEAVEVKWSV RMTLCAGICS YEGKGGMCSI RLSEPLLKLR PRKDLVETLL HEMIHAYLFV TNNDKDREGH GPEFCKHMHR INSLTGANIT VYHTFHDEVD EYRRHWWRCN GPCQHRPPYY GYVKRATNRE PSAHDYWWAE HQKTCGGTYI KIKEPENYSK KGKGKAKLGK EPVLAAENKG
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human SPRTN (NP_001010984.1).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Spartan
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Target
Spartan (C1orf124)
(Chromosome 1 Open Reading Frame 124 (C1orf124))
Alternative Name
SPRTN (C1orf124 Products )
Synonyms
Spartan antibody, c1orf124 antibody, C1orf124 antibody, DDDL1880 antibody, DVC1 antibody, PRO4323 antibody, dJ876B10.3 antibody, C28H1orf124 antibody, SprT-like N-terminal domain antibody, sprtn antibody, SPRTN antibody
Background
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.,SPRTN,C1orf124,DVC1,PRO4323,spartan,Epigenetics & Nuclear Signaling,SPRTN
Molecular Weight
24 kDa/29 kDa/55 kDa
Gene ID
83932
UniProt
Q9H040
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