LIMS2 antibody (AA 1-341)

Catalog No. ABIN6217146

Product Details anti-LIMS2 Antibody

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Binding Specificity: AA 1-341

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIMS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTGSNMSDAL ANAVCQRCQA RFSPAERIVN SNGELYHEHC FVCAQCFRPF PEGLFYEFEG RKYCEHDFQM LFAPCCGSCG EFIIGRVIKA MNNNWHPGCF RCELCDVELA DLGFVKNAGR HLCRPCHNRE KAKGLGKYIC QRCHLVIDEQ PLMFRSDAYH PDHFNCTHCG KELTAEAREL KGELYCLPCH DKMGVPICGA CRRPIEGRVV NALGKQWHVE HFVCAKCEKP FLGHRHYEKK GLAYCETHYN QLFGDVCYNC SHVIEGDVVS ALNKAWCVSC FSCSTCNSKL TLKNKFVEFD MKPVCKRCYE KFPLELKKRL KKLSELTSRK AQPKATDLNS A

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human LIMS2 (NP_001154875.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LIMS2

Target: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Alternative Name: LIMS2 (LIMS2 Products)

Synonyms: PINCH2 antibody, PINCH-2 antibody, LIMS1 antibody, LIM and senescent cell antigen like domains 2 antibody, LIM zinc finger domain containing 2 antibody, Lims2 antibody, LIMS2 antibody

Background: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.,LIMS2,LGMD2W,PINCH-2,PINCH2,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,LIMS2

Molecular Weight: 21 kDa/38 kDa/41 kDa

Gene ID: 55679

UniProt: Q7Z4I7

Pathways: Cell-Cell Junction Organization