RNF7 antibody (N-Term)

Catalog No. ABIN6242612

This Rabbit Polyclonal antibody specifically detects RNF7 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for RNF7 antibody (N-Term) (ABIN6242612)

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB52911

Product Details anti-RNF7 Antibody

Binding Specificity: AA 25-57, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the N-terminal region of human RNF7.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:8000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Alternative Name: RNF7

Background: Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Molecular Weight: 12683

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity