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RNF7 antibody

RNF7 Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7263303
$686.00
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  • Target See all RNF7 Antibodies
    RNF7 (Ring Finger Protein 7 (RNF7))
    Reactivity
    • 19
    • 11
    • 3
    Human
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF7 antibody is un-conjugated
    Application
    • 8
    • 7
    • 4
    • 3
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human RNF7 (NP_055060.1).
    Isotype
    IgG
  • Application Notes
    IF 1:20-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RNF7 (Ring Finger Protein 7 (RNF7))
    Alternative Name
    RNF7 (RNF7 Products)
    Synonyms
    CKBBP1 antibody, ROC2 antibody, SAG antibody, Rbx2 antibody, ring finger protein 7 antibody, RNF7 antibody, Rnf7 antibody
    Background
    The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Gene ID
    9616
    UniProt
    Q9UBF6
    Pathways
    Positive Regulation of Endopeptidase Activity
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