Integrin Alpha2b antibody (C-Term)

Catalog No. ABIN6242803

This anti-Integrin Alpha2b antibody is a Rabbit Polyclonal antibody detecting Integrin Alpha2b in WB. Suitable for Human.

Quick Overview for Integrin Alpha2b antibody (C-Term) (ABIN6242803)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB49132

Product Details anti-Integrin Alpha2b Antibody

Binding Specificity: AA 783-817, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITGA2B(Integrin alpha-IIb heavy chain) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 783-817 amino acids from the C-terminal region of human ITGA2B(Integrin alpha-IIb heavy chain).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B(Integrin alpha-IIb heavy chain)

Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Molecular Weight: 113377

UniProt: P08514

Pathways: Integrin Complex