DLG4 antibody (AA 548-579)

Catalog No. ABIN6243181

The Rabbit Polyclonal anti-DLG4 antibody (Clone RB54010) (ABIN6243181) specifically detects DLG4 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for DLG4 antibody (AA 548-579) (ABIN6243181)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB54010

Product Details anti-DLG4 Antibody

Binding Specificity: AA 548-579

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DLG4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 548-579 amino acids from human DLG4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Alternative Name: DLG4

Background: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

Molecular Weight: 80495

UniProt: P78352

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity