TXNRD1 antibody (AA 271-305)

Catalog No. ABIN6244290

The Rabbit Polyclonal anti-TXNRD1 antibody is suitable to detect TXNRD1 in samples from Human. It has been validated for WB.

Quick Overview for TXNRD1 antibody (AA 271-305) (ABIN6244290)

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNRD1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB56182

Product Details anti-TXNRD1 Antibody

Binding Specificity: AA 271-305

Predicted Reactivity: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TXNRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 271-305 amino acids from the Central region of human TXNRD1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Alternative Name: TXNRD1

Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Molecular Weight: 70906

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis