MMP2 antibody (AA 195-319)

Catalog No. ABIN6252229

The Mouse Monoclonal anti-MMP2 antibody is suitable to detect MMP2 in samples from Human. It has been validated for WB.

Quick Overview for MMP2 antibody (AA 195-319) (ABIN6252229)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: MMP2-1501

Product Details anti-MMP2 Antibody

Binding Specificity: AA 195-319

Purification: Protein G affinity chromatography

Immunogen: Amino acids 195-319 were used as the immunogen for the MMP2 antibody.

Isotype: IgG1

Application Details

Application Notes: WB: 0.5-1 μg/mL

The stated application concentrations are suggested starting amounts. Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Alternative Name: MMP2

Background: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.

Gene ID: 4313

UniProt: P08253

Pathways: Activation of Innate immune Response