×
For best experience we recommend to activate Javascript in your browser.
S1PR1 antibody (C-Term)
S1PR1
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-S1PR1 Antibody
(hide)
Target
See all S1PR1 Antibodies
S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Binding Specificity
All epitopes for S1PR1 antibodies
C-Term
Reactivity
All reactivities for S1PR1 antibodies
Human, Mouse, Rat
Host
All hosts for S1PR1 antibodies
Rabbit
Clonality
All clonalities for S1PR1 antibodies
Polyclonal
Conjugate
All conjugates for S1PR1 antibodies
This S1PR1 antibody is un-conjugated
Application
All applications for S1PR1 antibodies
Western Blotting (WB)
Purification
Protein A affinity chromatography
Immunogen
A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.
Isotype
IgG
Top Product
Discover our top product S1PR1 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Western blot: 4-6 μg/mL Provided assay concentrations are suggestions only, EDG1 antibody titration may be required for optimal results.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target Details for S1PR1
(hide)
Target
S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Alternative Name
EDG1 (S1PR1 Products )
Synonyms
CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody
Background
EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.
Gene ID
1901
UniProt
P21453
Pathways
Signaling Events mediated by VEGFR1 and VEGFR2
Recently viewed
(hide)