NKIRAS1 antibody

Catalog No. ABIN6252507

This Mouse Monoclonal antibody specifically detects NKIRAS1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NKIRAS1 antibody (ABIN6252507)

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This NKIRAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: NRAS285

Product Details anti-NKIRAS1 Antibody

Purification: Protein G purified antibody

Immunogen: A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Western blot: 5-10 μg/mL

Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for NKIRAS1

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Alternative Name: NKIRAS1

Background: NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.

NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.

Gene ID: 28512

UniProt: Q9NYS0