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Retinoblastoma Protein (Rb) antibody
Rb Protein
Reactivity: Human, Mouse
WB, IP, IHC (p)
Host: Mouse
Monoclonal
RB1-1754
unconjugated
Product Details anti-Retinoblastoma Protein (Rb) Antibody
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Target
See all Retinoblastoma Protein (Rb) (Rb Protein) Antibodies
Retinoblastoma Protein (Rb) (Rb Protein)
(Retinoblastoma Protein (Rb Protein))
Reactivity
All reactivities for Retinoblastoma Protein (Rb) antibodies
Human, Mouse
Host
All hosts for Retinoblastoma Protein (Rb) antibodies
Mouse
Clonality
All clonalities for Retinoblastoma Protein (Rb) antibodies
Monoclonal
Conjugate
All conjugates for Retinoblastoma Protein (Rb) antibodies
This Retinoblastoma Protein (Rb) antibody is un-conjugated
Application
All applications for Retinoblastoma Protein (Rb) antibodies
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Protein G affinity chromatography
Immunogen
A human recombinant protein was used as the immunogen for this Rb antibody.
Clone
RB1-1754
Isotype
IgG1 kappa
Top Product
Discover our top product Rb Protein Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 0.5-1 μg/mL IP: 1-2 μg/500 μg protein lysate IHC (FFPE): 1-2 μg/mL for 30 min at RT Titering of the Rb antibody may be required for optimal performance.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target Details for Retinoblastoma Protein (Rb)
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Target
Retinoblastoma Protein (Rb) (Rb Protein)
(Retinoblastoma Protein (Rb Protein))
Alternative Name
Retinoblastoma / Rb (Rb Protein Products )
Background
Recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
Gene ID
5925
UniProt
P06400
Pathways
Mitotic G1-G1/S Phases
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