Huntingtin antibody (AA 85-200)

Catalog No. ABIN6254174

The Goat Polyclonal anti-Huntingtin antibody has been validated for WB, IF and IHC (p). It is suitable to detect Huntingtin in samples from Human, Rat, Mouse, Rabbit, Monkey, Horse, Dog, Sheep, Pig, Hamster, Guinea Pig, Goat, Donkey, Cow, Chicken, Cat and Avian. There is 1 publication available.

Quick Overview for Huntingtin antibody (AA 85-200) (ABIN6254174)

Target: Huntingtin (HTT)

Reactivity: Human, Rat, Mouse, Rabbit, Monkey, Horse, Dog, Sheep, Pig, Hamster, Guinea Pig, Goat, Donkey, Cow, Chicken, Cat, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This Huntingtin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Huntingtin Antibody

Binding Specificity: AA 85-200

Specificity: Reacts huntingtin protein, amino acids 85-200. The antibody recognizes wild type and mutant huntingtin.

Characteristics: Huntingtin

Purification: epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 85 to 200 aa of human HTT produced in E. coli

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

References for anti-Huntingtin antibody (ABIN6254174)

Meunier, Merienne, Jollé, Déglon, Pellerin: "Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease." in: Glia, Vol. 64, Issue 11, pp. 1841-56, (2018) (PubMed).

Target Details for Huntingtin

Target: Huntingtin (HTT)

Alternative Name: HTT

Pathways: PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport