CHM antibody (C-Term)

Catalog No. ABIN6254221

This Goat Polyclonal antibody specifically detects CHM in WB. It exhibits reactivity toward Human, Rat, Mouse, Horse, Sheep, Rabbit, Pig, Monkey, Hamster, Guinea Pig, Goat, Donkey, Dog, Cow, Chicken, Cat and Avian.

Quick Overview for CHM antibody (C-Term) (ABIN6254221)

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Reactivity: Human, Rat, Mouse, Horse, Sheep, Rabbit, Pig, Monkey, Hamster, Guinea Pig, Goat, Donkey, Dog, Cow, Chicken, Cat, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This CHM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHM Antibody

Binding Specificity: C-Term

Purpose: Anti-REP1

Sequence: IIFDGDSLQP EASESSAIPE ANSETFKEST NLGNLEESSE

Specificity: Detects endogenous Rep1 and in transfected cells by Western blot.

Characteristics: Choroideremia (Rab escort protein 1)

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human Rep1 produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for CHM

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Alternative Name: REP1

Background:

REP1 is the component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Mutations in this protein are a cause of a type of retinal degeneration, called choroideremia.

CHM, choroideremia protein, DXS540, GGTA, HSD-32, RP1-93L7.1, rab escort protein 1, Rab geranylgeranyltransferase component A, REP-1, TCD antibody.

Pathways: Sensory Perception of Sound