CHM antibody (AA 1-653) (Biotin)

Catalog No. ABIN7166974

Product Details anti-CHM Antibody (Biotin)

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Binding Specificity: AA 1-653

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHM antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Rab proteins geranylgeranyltransferase component A 1 protein (1-653AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHM

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Alternative Name: CHM (CHM Products)

Synonyms: CHM antibody, REP1 antibody, DXS540 antibody, GGTA antibody, HSD-32 antibody, REP-1 antibody, TCD antibody, DKFZp459K2154 antibody, tcd antibody, ggta antibody, rep-1 antibody, dxs540 antibody, hsd-32 antibody, MGC68578 antibody, Rep-1 antibody, chm antibody, chm-a antibody, chm-b antibody, chml antibody, CHM, Rab escort protein 1 antibody, choroideremia (Rab escort protein 1) antibody, choroideremia (Rab escort protein 1) L homeolog antibody, choroidermia (RAB escort protein 1) antibody, choroideremia (Rab escort protein 1) S homeolog antibody, CHM antibody, chm antibody, chm.L antibody, Chm antibody, chm.S antibody

Background:

Background: Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins, this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.

Aliases: dy, Chm antibody, Choroideraemia protein antibody, Choroideremia antibody, DXS540 antibody, FLJ38564 antibody, GGTA antibody, HSD 32 antibody, MGC102710 antibody, Rab escort protein 1 antibody, Rab geranylgeranyltransferase component A antibody, Rab proteins geranylgeranyltransferase component A 1 antibody, RAE1_HUMAN antibody, REP 1 antibody, REP-1 antibody, REP1 antibody, TCD antibody, TCD protein antibody

UniProt: P24386

Pathways: Sensory Perception of Sound