CD4 antibody

Catalog No. ABIN6254232

This anti-CD4 antibody is a Goat Polyclonal antibody detecting CD4 in WB and IHC. Suitable for Human, Mouse, Rat, Chicken, Monkey, Dog, Pig, Rabbit, Cat, Cow, Sheep, Guinea Pig, Goat, Horse, Avian, Donkey and Hamster. This Primary Antibody has been cited in 1 publication.

Quick Overview for CD4 antibody (ABIN6254232)

Key Features:

• High quality CD4 Primary Antibody for the detection of CD4.
• Reliable product with high standard validation data

Target: CD4

Reactivity: Human, Mouse, Rat, Chicken, Monkey, Dog, Pig, Rabbit, Cat, Cow, Sheep, Guinea Pig, Goat, Horse, Avian, Donkey, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This CD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CD4 Antibody

Specificity: Using spleen lysate detects a 52 kDa band by Western blot.

Characteristics: CD4 Molecule

Purification: epitope affinity purified

Immunogen: Purified recombinant peptide derived from within 50 to 235 aa, corresponding to the external domain of human CD4 produced in E. coli.

Isotype: IgG

Product Specific Information:

What can the CD4 Antibody ABIN6254232 be used for?: This polyclonal CD4 Antibody detects CD4. The CD4 Antibody has been validated for various applications and can be used for the detection of CD4 and derivatives by Western Blotting, Immunohistochemistry.

What validation data is available for this CD4 Antibody?: The primary antibody is referenced in 1 publications and is characterized by a proven, very high reliability. It has currently 6 product images that show its performance in a variety of applications. The product is currently available in 600 μg quantity. CD4 Antibody for the detection of CD4 and derivatives.

What is the function of CD4?: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

References for anti-CD4 antibody (ABIN6254232)

Helsby, Leader, Fenn, Gulsen, Bryant, Doughton, Sharpe, Whitley, Caunt, James, Pope, Kelly, Chalmers: "CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited." in: BMC cell biology, Vol. 15, pp. 6, (2014) (PubMed).

Target Details for CD4

Target: CD4

Alternative Name: CD4

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events