Calnexin antibody (pSer564)
Quick Overview for Calnexin antibody (pSer564) (ABIN6255414)
Target
See all Calnexin (CANX) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer564
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Specificity
- Phospho-Calnexin(Ser564) Antibody detects endogenous levels of Calnexin.
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Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Calnexin around the phosphorylation site of Ser564.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
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Expiry Date
- 12 months
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- Calnexin (CANX)
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Alternative Name
- Calnexin
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Background
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Description: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Gene: CANX
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Molecular Weight
- 90kDa
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Gene ID
- 821
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UniProt
- P27824
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Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
Target
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