EPOR antibody (pTyr368)

Catalog No. ABIN6255901

The Rabbit Polyclonal anti-EPOR antibody (ABIN6255901) specifically detects EPOR in WB, ELISA, ICC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for EPOR antibody (pTyr368) (ABIN6255901)

Target: EPOR (Erythropoietin Receptor (EPOR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPOR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-EPOR Antibody

Binding Specificity: pTyr368

Specificity: Phospho-Epo-R (Tyr368) Antibody detects endogenous levels of Epo-R only when phosphorylated at Tyrosine 368.

Predicted Reactivity: Pig,Sheep,Dog

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Epo-R around the phosphorylation site of Tyr368.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for EPOR

Target: EPOR (Erythropoietin Receptor (EPOR))

Alternative Name: EPOR

Background:

Description: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Gene: EPOR

Molecular Weight: 55kDa

Gene ID: 2057

UniProt: P19235

Pathways: JAK-STAT Signaling