FGF19 antibody (C-Term)

Catalog No. ABIN6257192

This Rabbit Polyclonal antibody specifically detects FGF19 in WB, ELISA and IHC. It exhibits reactivity toward Human and Rat.

Quick Overview for FGF19 antibody (C-Term) (ABIN6257192)

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FGF19 Antibody

Binding Specificity: C-Term

Specificity: FGF19 Antibody detects endogenous levels of total FGF19.

Predicted Reactivity: Pig,Zebrafish,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FGF19, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for FGF19

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Alternative Name: FGF19

Background:

Description: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.

Gene: FGF19

Molecular Weight: 24 kDa,

Gene ID: 9965

UniProt: O95750

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway