GRID2 antibody (C-Term)

Catalog No. ABIN6257247

Product Details anti-GRID2 Antibody

Target: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRID2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Specificity: GRID2 Antibody detects endogenous levels of total GRID2.

Predicted Reactivity: Pig,Zebrafish,Sheep,Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GRID2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GRID2

Target: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Alternative Name: GRID2 (GRID2 Products)

Synonyms: GluD2 antibody, glurd2 antibody, si:rp71-1l7.1 antibody, GRID2 antibody, B230104L07Rik antibody, GluRdelta2 antibody, Lc antibody, Lc antibody, MMS10-AC antibody, Ms10ac antibody, cpr antibody, ho antibody, nmf408 antibody, tpr antibody, glutamate receptor, ionotropic, delta 2 antibody, glutamate receptor ionotropic, delta-2 antibody, glutamate ionotropic receptor delta type subunit 2 antibody, grid2 antibody, LOC704787 antibody, GRID2 antibody, Grid2 antibody, LOC536367 antibody

Background:

Description: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex (PubMed:27418511).

Gene: GRID2

Molecular Weight: 113 kDa

Gene ID: 2895

UniProt: O43424

Pathways: Synaptic Membrane