Myocardin antibody (AA 200-280)

Catalog No. ABIN7229814

This Rabbit Polyclonal antibody specifically detects Myocardin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Myocardin antibody (AA 200-280) (ABIN7229814)

Target: Myocardin (MYOCD)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myocardin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Myocardin Antibody

Binding Specificity: AA 200-280

Purpose: Rabbit Anti-MYCD Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MYCD protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MYCD protein at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Myocardin

Target: Myocardin (MYOCD)

Alternative Name: MYCD

Background: MyocardinMYOCD encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. MYOCD (Myocardin) is a Protein Coding gene. Among its related pathways are HOP Signaling and SRF and miRs in Smooth Muscle Differentiation and Proliferation.

Molecular Weight: 103kD

Gene ID: 93649

UniProt: Q8IZQ8

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development