ARHGEF16 antibody (Internal Region)

Catalog No. ABIN6257894

Product Details anti-ARHGEF16 Antibody

Target: ARHGEF16 (rho Guanine Nucleotide Exchange Factor (GEF) 16 (ARHGEF16))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ARHGEF16 Antibody detects endogenous levels of total ARHGEF16.

Predicted Reactivity: Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ARHGEF16, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ARHGEF16

Target: ARHGEF16 (rho Guanine Nucleotide Exchange Factor (GEF) 16 (ARHGEF16))

Alternative Name: ARHGEF16 (ARHGEF16 Products)

Synonyms: GEF16 antibody, NBR antibody, Rho guanine nucleotide exchange factor 16 antibody, Rho guanine nucleotide exchange factor (GEF) 16 antibody, ARHGEF16 antibody, arhgef16 antibody, Arhgef16 antibody

Background:

Description: Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.

Gene: ARHGEF16

Molecular Weight: 80 kDa

Gene ID: 27237

UniProt: Q5VV41

Pathways: Neurotrophin Signaling Pathway