CENPO antibody (Internal Region)

Catalog No. ABIN6258491

Product Details anti-CENPO Antibody

Target: CENPO (Centromere Protein O (CENPO))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPO antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: CENPO Antibody detects endogenous levels of total CENPO.

Predicted Reactivity: Pig

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CENPO, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CENPO

Target: CENPO (Centromere Protein O (CENPO))

Alternative Name: CENPO (CENPO Products)

Synonyms: cenpo antibody, MGC144960 antibody, CENPO antibody, MAJ23.70 antibody, MAJ23_70 antibody, zgc:171667 antibody, CENP-O antibody, ICEN-36 antibody, MCM21R antibody, 2810429O05Rik antibody, 8430427C03Rik antibody, D12Ertd482e antibody, centromere protein O antibody, cenpo antibody, CENPO antibody, AT5G10710 antibody, Cenpo antibody

Background:

Description: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.

Gene: CENPO

Molecular Weight: 34 kDa

Gene ID: 79172

UniProt: Q9BU64