SLC4A11 antibody (Internal Region)

Catalog No. ABIN6258559

Product Details anti-SLC4A11 Antibody

Target: SLC4A11 (Solute Carrier Family 4, Sodium Borate Transporter, Member 11 (SLC4A11))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC4A11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: SLC4A11 Antibody detects endogenous levels of total SLC4A11.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SLC4A11, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC4A11

Target: SLC4A11 (Solute Carrier Family 4, Sodium Borate Transporter, Member 11 (SLC4A11))

Alternative Name: SLC4A11 (SLC4A11 Products)

Synonyms: NaBC1 antibody, si:dkey-12j14.4 antibody, AI503023 antibody, BTR1 antibody, CDPD1 antibody, CHED2 antibody, NABC1 antibody, dJ794I6.2 antibody, solute carrier family 4 member 11 antibody, solute carrier family 4 member 11 L homeolog antibody, solute carrier family 4, sodium borate transporter, member 11 antibody, solute carrier family 4, sodium bicarbonate transporter-like, member 11 antibody, Slc4a11 antibody, SLC4A11 antibody, slc4a11.L antibody, slc4a11 antibody

Background:

Description: Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration (By similarity). Involved in borate homeostasis. In the absence of borate, it functions as a Na+ and OH-(H+) channel. In the presence of borate functions as an electrogenic Na+ coupled borate cotransporter.

Gene: SLC4A11

Molecular Weight: 100 kDa

Gene ID: 83959

UniProt: Q8NBS3

Pathways: Proton Transport