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RPA2 antibody (Internal Region)

This Rabbit Polyclonal antibody specifically detects RPA2 in WB, IHC, IF and ICC. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN6259178
$441.17
Plus shipping costs $50.00
Shipping to: United States
Delivery in 11 to 13 Business Days

Quick Overview for RPA2 antibody (Internal Region) (ABIN6259178)

Target

See all RPA2 Antibodies
RPA2 (Replication Protein A2, 32kDa (RPA2))

Reactivity

  • 210
  • 64
  • 44
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 164
  • 48
  • 2
Rabbit

Clonality

  • 119
  • 95
Polyclonal

Conjugate

  • 103
  • 12
  • 8
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This RPA2 antibody is un-conjugated

Application

  • 167
  • 60
  • 39
  • 38
  • 36
  • 32
  • 28
  • 26
  • 26
  • 17
  • 7
  • 5
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Binding Specificity

    • 43
    • 26
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    Purpose

    RPA2 Antibody

    Specificity

    RPA2 Antibody detects endogenous levels of total RPA2.

    Predicted Reactivity

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human RPA2, corresponding to a region within the internal amino acids.

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C. Stable for 12 months from date of receipt.

    Expiry Date

    12 months
  • Target

    RPA2 (Replication Protein A2, 32kDa (RPA2))

    Alternative Name

    RPA2

    Background

    Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).

    Gene: POLR1B

    Molecular Weight

    128 kDa

    Gene ID

    84172

    UniProt

    Q9H9Y6

    Pathways

    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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