ABI2 antibody (Internal Region)

Catalog No. ABIN6259703

Product Details anti-ABI2 Antibody

Target: ABI2 (Abl-Interactor 2 (ABI2))

Binding Specificity: Internal Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: ABI2 Antibody detects endogenous levels of total ABI2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ABI2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Alternative Name: ABI2 (ABI2 Products)

Synonyms: ABI-2 antibody, ABI2B antibody, AIP-1 antibody, AblBP3 antibody, SSH3BP2 antibody, argBPIA antibody, argBPIB antibody, 8430425M24Rik antibody, AI839867 antibody, C130078H13 antibody, abl interactor 2 antibody, abl-interactor 2 antibody, ABI2 antibody, abi2 antibody, Abi2 antibody

Background:

Description: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).

Gene: ABI2

Molecular Weight: 80 kDa

Gene ID: 10152

UniProt: Q9NYB9